Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | HPGD | P15428 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956785 | 0.87 | MTNR1A (0.51) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL1324265 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL11260725 | 0.82 | KDM4E (0.50) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL3976428 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL10383094 | 0.80 | MAOB (0.55) | ALDH1A1KDM4EMAPTMAOBGAA | |
| SCHEMBL10987931 | 0.76 | MTNR1A (0.44) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL19630730 | 0.75 | MTNR1A (0.57) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL20893351 | 0.75 | MAPT (0.48) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL8555827 | 0.75 | MTNR1A (0.56) | ALDH1A1KDM4EHPGDRAB9ANPC1 | |
| SCHEMBL6130765 | 0.75 | MTNR1A (0.52) | ALDH1A1KDM4EHPGDRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |