Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260725 | 0.87 | KDM4E (0.50) | MTNR1AMTNR1BL3MBTL1TDP1KDM4E | |
| SCHEMBL7943979 | 0.87 | ALDH1A1 (0.50) | MTNR1AMTNR1BL3MBTL1TDP1KDM4E | |
| SCHEMBL2811677 | 0.81 | KDM4E (0.49) | MTNR1AMTNR1BCHEK1METGSK3B | |
| SCHEMBL6130765 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1BL3MBTL1TDP1KDM4E | |
| SCHEMBL8555827 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BDYRK1ANR4A2L3MBTL1 | |
| SCHEMBL10964341 | 0.76 | MTNR1A (0.47) | MTNR1AMTNR1BL3MBTL1TDP1KDM4E | |
| SCHEMBL9220938 | 0.75 | MTNR1A (0.49) | MTNR1AMTNR1BCHEK1METGSK3B | |
| SCHEMBL22809961 | 0.75 | L3MBTL1 (0.59) | MTNR1ANR4A2L3MBTL1TDP1KDM4E | |
| SCHEMBL9209256 | 0.74 | MTNR1A (0.48) | MTNR1AMTNR1BDYRK1ADYRK1BL3MBTL1 | |
| SCHEMBL9220714 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1BNR4A2L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |