SCHEMBL7944156

SCHEMBL7944156

C#Cc1cccc(S(=O)(=O)c2ccccc2)c1C#C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.46
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
HSD11B1 P28845 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
FEN1 P39748 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746462 0.86 CA12 (0.46) HTR6KMT2AALDH1A1LMNAHPGD
SCHEMBL2746856 0.85 HTR6 (0.52) HTR6KMT2AALDH1A1LMNAHPGD
SCHEMBL8637433 0.76 HTR6 (0.44) HTR6ALDH1A1TSHRHTTGAA
SCHEMBL8080841 0.72 HTR6 (0.72) HTR6KMT2AALDH1A1TSHRHTT
SCHEMBL7780736 0.72 HTR6 (0.53) HTR6KMT2AALDH1A1LMNAHPGD
SCHEMBL14159522 0.71 MET (0.48) HTR6KMT2ATSHRHTT
SCHEMBL1146161 0.71 HSD11B1 (0.59) HTR6KMT2AALDH1A1LMNAHPGD
SCHEMBL30125526 0.70 MYC (0.40) ALDH1A1TSHRHTTPOLBGAA
SCHEMBL1920956 0.70 MYC (0.40) ALDH1A1TSHRHTTPOLBGAA
SCHEMBL1514985 0.70 CYP1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834499-B1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK & CHEMICALS (JP) 2001-07-25 EP disclosed
EP-0834499-A1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-04-08 EP disclosed