Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288088 | 0.97 | FDPS (0.33) | FDPSDPP7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2563000 | 0.84 | ALDH1A1 (0.37) | HRH3ALDH1A1MAPT | |
| SCHEMBL28226868 | 0.84 | SIGMAR1 (0.36) | — | |
| SCHEMBL9695357 | 0.82 | — | — | |
| SCHEMBL10880835 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL2673825 | 0.80 | SLC6A2 (0.33) | CYP2D6 | |
| SCHEMBL9669586 | 0.77 | ACHE (0.32) | HRH3ALDH1A1 | |
| SCHEMBL7330270 | 0.76 | SLC6A3 (0.38) | HRH3 | |
| SCHEMBL19334589 | 0.74 | SLC6A4 (0.39) | FDPSDPP7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3309623 | 0.74 | SLC6A4 (0.39) | FDPSDPP7CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262046-B1 | Azetidinylpropylpiperidine derivatives, intermediates and use as tachykinin antagonists | PFIZER INC. | 2001-07-17 | — | — | US | disclosed |
| US-6262046-B1 | Azetidinylpropylpiperidine derivatives, intermediates and use as tachykinin antagonists | PFIZER INC. | 2001-07-17 | — | — | US | disclosed |
| EP-1023285-A1 | AZETIDINYLPROPYLPIPERIDINE DERIVATIVES, INTERMEDIATES AND USE AS TACHYKININ ANTAGONISTS | Pfizer Limited (GB) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999001451-A1 | AZETIDINYLPROPYLPIPERIDINE DERIVATIVES, INTERMEDIATES AND USE AS TACHYKININ ANTAGONISTS | PFIZER LIMITED (GB) | 1999-01-14 | — | — | WO | disclosed |