Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951355 | 0.80 | MEN1 (0.65) | OPRM1OPRL1MEN1KMT2AHTR5A | |
| SCHEMBL7952672 | 0.80 | MEN1 (0.65) | OPRM1OPRL1MEN1KMT2AHTR5A | |
| SCHEMBL7226427 | 0.80 | MEN1 (0.65) | OPRM1OPRL1MEN1KMT2AHTR5A | |
| SCHEMBL7251987 | 0.78 | ALOX15 (0.51) | OPRM1OPRL1MEN1KMT2ATAAR1 | |
| Hydrochloric Acid SCHEMBL8110478 | 0.77 | OPRM1 (0.45) | OPRM1OPRL1MEN1KMT2ATAAR1 | |
| SCHEMBL7233178 | 0.76 | ALOX15 (0.46) | OPRM1OPRL1MEN1KMT2ATAAR1 | |
| SCHEMBL7979601 | 0.72 | ALDH1A1 (0.51) | TAAR1ALDH1A1GRIN2B | |
| SCHEMBL7951338 | 0.72 | MEN1 (0.62) | OPRM1OPRL1MEN1KMT2AHTR5A | |
| SCHEMBL423267 | 0.70 | OPRL1 (0.60) | OPRM1OPRL1MEN1KMT2AMAOA | |
| SCHEMBL7944447 | 0.69 | MEN1 (0.47) | OPRM1OPRL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228861-B1 | BENIGN PROSTATIC HYPERPLASIA; ANTICHOLESTEROL AGENTS; IMPOTENCY; INTRAOCULAR PRESSURE; ANTIARRHYTHMIA AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-05-08 | — | — | US | disclosed |
| US-6172066-B1 | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-0866708-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0866708-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997017969-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |