Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 9/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830712 | 0.85 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL7813094 | 0.84 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL7827120 | 0.73 | TLR7 (0.35) | CRHR1 | |
| SCHEMBL7823112 | 0.70 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL6894855 | 0.69 | — | — | |
| SCHEMBL7947126 | 0.66 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL7820032 | 0.66 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL6775364 | 0.65 | ALOX15 (0.35) | — | |
| SCHEMBL7820028 | 0.65 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL6780509 | 0.62 | MEN1 (0.39) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124300-A | Aryloxy- and arylthio- fused pyridines and pyrimidines and derivatives | DUPONT PHARMACEUTICALS (US) | 2000-09-26 | — | — | US | claimed |
| US-6258809-B1 | NERVOUS SYSTEM DISORDERS, ANTIDEPRESSANTS AND PSYCHIATRY | DUPONT PHARMACEUTICALS COMPANY | 2001-07-10 | — | — | US | disclosed |
| US-6124300-A | Aryloxy- and arylthio- fused pyridines and pyrimidines and derivatives | DUPONT PHARMACEUTICALS (US) | 2000-09-26 | — | — | US | disclosed |