Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 10/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292056 | 0.87 | MAOA (0.48) | HTR7ADRA1DADRA1AADRA1BMAOA | |
| SCHEMBL8070478 | 0.81 | TSHR (0.43) | HTR7ADRA1DADRA1AADRA1BMAOA | |
| SCHEMBL6262900 | 0.81 | HRH4 (0.35) | HTR7ADRA1DADRA1AADRA1BHTR6 | |
| SCHEMBL7751584 | 0.79 | MAOA (0.38) | HTR7ADRA1DADRA1AADRA1BMAOA | |
| SCHEMBL7723310 | 0.78 | HTR7 (0.43) | HTR7ADRA1DADRA1AADRA1BHTR2A | |
| SCHEMBL7113219 | 0.78 | LMNA (0.38) | ALDH1A1LMNA | |
| SCHEMBL6262182 | 0.76 | TLR8 (0.33) | HTR7HTR2AHTR6 | |
| SCHEMBL9291907 | 0.75 | ADRB2 (0.41) | HTR7ADRA1DADRA1AADRA1BMAOA | |
| SCHEMBL9291585 | 0.73 | LMNA (0.40) | ALDH1A1LMNA | |
| SCHEMBL19336345 | 0.73 | HTR7 (0.38) | HTR7ADRA1DADRA1AADRA1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001043546-A2 | COMBINATIONS OF HERBICIDAL ALKYLAZINES AND SAFENERS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |