Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656092 | 0.83 | CTSS (0.45) | CTSBCTSSCTSKPTPN1 | |
| SCHEMBL4656090 | 0.83 | CTSS (0.45) | CTSBCTSSCTSKPTPN1 | |
| SCHEMBL4657429 | 0.80 | NPC1 (0.39) | ALDH1A1KMT2ABCHEACHEOPRM1 | |
| SCHEMBL4657436 | 0.80 | NPC1 (0.39) | ALDH1A1KMT2ABCHEACHEOPRM1 | |
| SCHEMBL4657546 | 0.80 | ABCB1 (0.40) | ACACBALDH1A1KMT2ACTSBCTSS | |
| SCHEMBL7947407 | 0.79 | ADRA1A (0.33) | ACACB | |
| SCHEMBL4657437 | 0.75 | KMT2A (0.38) | ACACBALDH1A1KMT2ANR1H4BCHE | |
| SCHEMBL4657426 | 0.75 | KMT2A (0.38) | ACACBALDH1A1KMT2ANR1H4BCHE | |
| SCHEMBL3995019 | 0.70 | PTPRB (0.38) | — | |
| SCHEMBL7271138 | 0.69 | HSP90AA1 (0.38) | ALDH1A1ITGB1ITGA4NR1H4MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255285-B1 | GASTROINTESTINAL DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-07-03 | — | — | US | disclosed |