Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656090 | 0.80 | CTSS (0.45) | — | |
| SCHEMBL4656092 | 0.80 | CTSS (0.45) | — | |
| SCHEMBL7947409 | 0.79 | ACACB (0.33) | ACACB | |
| SCHEMBL4657429 | 0.77 | NPC1 (0.39) | — | |
| SCHEMBL4657436 | 0.77 | NPC1 (0.39) | — | |
| SCHEMBL4657546 | 0.75 | ABCB1 (0.40) | ACACB | |
| SCHEMBL4657375 | 0.67 | ACACB (0.38) | ADRA1APOLBMAPTACACB | |
| SCHEMBL4657437 | 0.66 | KMT2A (0.38) | ACACB | |
| SCHEMBL4657426 | 0.66 | KMT2A (0.38) | ACACB | |
| SCHEMBL3989091 | 0.66 | REN (0.34) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255285-B1 | GASTROINTESTINAL DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-07-03 | — | — | US | disclosed |