Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 10/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733694 | 0.83 | GPR55 (0.50) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL7947228 | 0.81 | HTR1A (0.73) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL7961634 | 0.78 | HTR1A (0.65) | RAB9ANPC1TDP1L3MBTL1TSHR | |
| SCHEMBL7956997 | 0.78 | DRD2 (0.58) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL7954885 | 0.77 | NPC1 (0.63) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL2089122 | 0.77 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL7961648 | 0.77 | HTR1A (0.63) | RAB9ANPC1TDP1L3MBTL1TSHR | |
| SCHEMBL11623649 | 0.75 | TSHR (0.54) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL11624188 | 0.74 | TSHR (0.53) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL11626261 | 0.74 | NOTUM (0.44) | RAB9ANPC1SMN1; SMN2MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |