SCHEMBL7947550

SCHEMBL7947550

COCCCCC(C)(C)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.43
CYP4A11 Q02928 1/20 0.43
ALDH1A1 P00352 4/20 0.42
TSHR P16473 2/20 0.38
ARG1 P05089 1/20 0.38
ARG2 P78540 1/20 0.38
DGAT1 O75907 1/20 0.34
ACLY P53396 1/20 0.34
RECQL P46063 1/20 0.34
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
KDM4E B2RXH2 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
ACAT1 P24752 1/20 0.32
SOAT1 P35610 1/20 0.32
THRB P10828 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13355267 0.94 CYP4F2 (0.40) CYP4F2CYP4A11ALDH1A1TSHRARG1
SCHEMBL20375533 0.88 CYP4F2 (0.43) CYP4F2CYP4A11TSHRDGAT1ACLY
SCHEMBL6256870 0.86 CYP4F2 (0.42) CYP4F2CYP4A11TSHRDGAT1ACLY
SCHEMBL5527551 0.86 CYP4F2 (0.46) CYP4F2CYP4A11ALDH1A1TSHRDGAT1
SCHEMBL12803851 0.85 DGAT1 (0.38) CYP4F2CYP4A11ALDH1A1TSHRARG1
SCHEMBL3901988 0.82 CYP4F2 (0.42) CYP4F2CYP4A11ALDH1A1TSHRARG1
SCHEMBL22016456 0.81 ACLY (0.46) CYP4F2CYP4A11TSHRACLYACACB
SCHEMBL6371095 0.81 CYP4A11 (0.63) CYP4F2CYP4A11TSHRARG2DGAT1
SCHEMBL1996919 0.81 CYP4F2 (0.48) CYP4F2CYP4A11TSHRKDM4ETP53
SCHEMBL31053497 0.80 ALDH1A1 (0.39) CYP4F2CYP4A11ALDH1A1TSHRARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265440-B1 STOMACH ULCERS R-TECH UENO, LTD. (JP) 2001-07-24 US disclosed
US-5886034-A ANTIULCER AGENTS KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) 1999-03-23 US disclosed
US-5428062-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1995-06-27 US disclosed
US-5380709-A Prostaglandins E and anti ulcers containing same K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1995-01-10 US disclosed
US-5284858-A Prostaglandins E and anti ulcers containing same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1994-02-08 US disclosed
US-5225439-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1993-07-06 US disclosed
US-5166174-A For duodenal ulcers or gastric ulcers K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-11-24 US disclosed
EP-0284180-B1 PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-08-19 EP disclosed
EP-0284180-A1 Prostaglandins E and anti ulcers containing same Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-09-28 EP disclosed