Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | FADS1 | O60427 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950787 | 0.84 | HTT (0.59) | MAPTRAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7939052 | 0.81 | ALDH1A1 (0.49) | MAPTHPGDSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7945542 | 0.80 | ALDH1A1 (0.67) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7946627 | 0.78 | KMT2A (0.59) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7939040 | 0.78 | NPC1 (0.56) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6816002 | 0.77 | MAPT (0.59) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7938939 | 0.76 | MAPT (0.56) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6816009 | 0.73 | KDM4E (0.53) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7945458 | 0.73 | MAPT (0.48) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL7939128 | 0.73 | LMNA (0.52) | MAPTNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |