Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947629 | 0.84 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6813918 | 0.79 | HTT (0.61) | HTTMEN1KMT2AMAPTGAA | |
| SCHEMBL7939052 | 0.78 | ALDH1A1 (0.49) | HTTMEN1KMT2AMAPTGAA | |
| SCHEMBL7945542 | 0.77 | ALDH1A1 (0.67) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL6813923 | 0.75 | HTT (0.56) | HTTMEN1KMT2AMAPTGAA | |
| SCHEMBL7946627 | 0.75 | KMT2A (0.59) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL7939040 | 0.75 | NPC1 (0.56) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL27488497 | 0.74 | CRHBP (0.67) | HTTMEN1KMT2AMAPTGAA | |
| SCHEMBL3595597 | 0.73 | HTT (0.70) | HTTMEN1KMT2AMAPTGAA | |
| SCHEMBL7691380 | 0.73 | CYP3A4 (0.65) | HTTMEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |