Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939128 | 0.90 | LMNA (0.52) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7945458 | 0.88 | MAPT (0.48) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7950802 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL7946708 | 0.84 | MAPT (0.45) | MEN1KMT2AMAPTLMNAPYGL | |
| SCHEMBL7938904 | 0.82 | SHMT2 (0.44) | ALDH1A1MEN1KMT2AMAPTPYGL | |
| SCHEMBL7947629 | 0.81 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7939140 | 0.80 | KMT2A (0.43) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL7945326 | 0.80 | KMT2A (0.41) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL4555009 | 0.79 | MAPT (0.76) | ALDH1A1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7950787 | 0.78 | HTT (0.59) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |