Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14139155 | 0.79 | HTT (0.60) | HTTKMT2AHPGDMEN1SMN1; SMN2 | |
| SCHEMBL16827451 | 0.74 | PYCR1 (0.43) | SLC6A4HTTKMT2AHPGDMEN1 | |
| SCHEMBL12496273 | 0.74 | PYCR1 (0.43) | HTTKMT2AHPGDMEN1SMN1; SMN2 | |
| SCHEMBL7191364 | 0.72 | AKR1B10 (0.53) | HTTKMT2AHPGDMEN1SMN1; SMN2 | |
| SCHEMBL11128804 | 0.67 | TRPA1 (0.42) | KMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL7820988 | 0.67 | SLC6A4 (0.34) | SLC6A4SLC6A2SLC6A3KMT2AMEN1 | |
| SCHEMBL27259071 | 0.66 | TAAR1 (0.46) | SMN1; SMN2 | |
| SCHEMBL9105772 | 0.65 | HTT (0.35) | HTTKMT2AHPGDMEN1SMN1; SMN2 | |
| SCHEMBL4439253 | 0.65 | ERN1 (0.45) | SLC6A4SLC6A2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11127533 | 0.64 | TSHR (0.43) | HTTKMT2AHPGDMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |