Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.44 |
| ▸ | PGK2 | P07205 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4273303 | 0.77 | PGK1 (0.41) | PGK1PGK2KDM4ETSHRTDP1 | |
| SCHEMBL29860803 | 0.77 | PGK1 (0.41) | PGK1PGK2KDM4ETSHRTDP1 | |
| SCHEMBL19540540 | 0.77 | ADRB1 (0.57) | PGK1PGK2ADRB1 | |
| SCHEMBL22931517 | 0.77 | KDM4E (0.64) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL28518014 | 0.77 | KCNH2 (0.39) | PGK1PGK2ADRB1 | |
| SCHEMBL3298262 | 0.75 | PGK1 (0.50) | PGK1PGK2 | |
| SCHEMBL24453820 | 0.73 | GABRA1 (0.39) | KDM4ETSHR | |
| SCHEMBL11360231 | 0.72 | F2 (0.46) | KDM4ETSHRTDP1 | |
| SCHEMBL9232328 | 0.71 | UGT2B7 (0.39) | PGK1PGK2TSHRTDP1ADRB1 | |
| SCHEMBL31085146 | 0.71 | UGT2B7 (0.39) | PGK1PGK2TSHRTDP1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873256-A | Crosslinked polydimethylsiloxane elastomer material and preparation method thereof | 四川大学 | 2023-03-31 | — | — | CN | claimed |
| WO-2017103545-A1 | LANTHANIDE COMPLEXES FOR CRYSTALLISING BIOLOGICAL MACROMOLECULES AND DETERMINING THE CRYSTALLOGRAPHIC STRUCTURE THEREOF | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-22 | — | — | WO | disclosed |
| US-6329523-B1 | FOR ANTIBACTERIAL PHARMACEUTICAL USE, USEFUL FOR IDENTIFYING METAL CHELATING SPECIES FOR ?HEAVY METAL? THERAPY; IMAGING AGENTS | ISIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| US-6197965-B1 | POLYARYLALKYLAMINO-SUBSTITUED PYRIDINE DERIVATIVES; DRUGS, MEDICINE, DIAGNOSTICS | ISIS PHARMACEUTICALS, INC. | 2001-03-06 | — | — | US | disclosed |
| US-6077954-A | COMPOUNDS ARE CONSTRUCTED TO INCLUDE A CENTRAL AROMATIC, ALIPHATIC, OR HETEROCYCLIC RING SYSTEM. ATTACHED TO THE CENTRAL RING SYSTEM ARE TWO LINEAR GROUPS HAVING NITROGENOUS MOIETIES THAT ARE DERIVATIZED WITH CHEMICAL FUNCTIONAL GROUPS. | ISIS PHARMACEUTICALS, INC. (US) | 2000-06-20 | — | — | US | disclosed |