SCHEMBL7948432

SCHEMBL7948432

CCOc1ccc2c(c1)CCC(O)C2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 7/20 0.48
DRD3 P35462 7/20 0.48
PPARD Q03181 1/20 0.45
NQO2 P16083 1/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
CYP26A1 O43174 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
DRD4 P21917 2/20 0.42
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
CYP19A1 P11511 1/20 0.40
NQO1 P15559 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7958191 0.82 DRD2 (0.58) DRD2DRD3MTNR1AMTNR1BCYP26A1
SCHEMBL18983590 0.80 HRH3 (0.59)
SCHEMBL10071512 0.77 NQO1 (0.54) CYP11B1CYP11B2POLBTDP1CYP19A1
Hydrochloric Acid SCHEMBL11492258 0.77 DRD2 (0.53) DRD2DRD3NQO2MTNR1AMTNR1B
SCHEMBL4001498 0.76 DRD2 (0.66) DRD2DRD3MTNR1AMTNR1BCYP26A1
SCHEMBL6403014 0.76 DRD2 (0.66) DRD2DRD3MTNR1AMTNR1BCYP26A1
SCHEMBL629692 0.76 DRD2 (0.66) DRD2DRD3MTNR1AMTNR1BCYP26A1
SCHEMBL13590243 0.76 DRD3 (0.47) DRD2DRD3CYP26A1CYP1A2CYP11B1
SCHEMBL25637281 0.75 CHRNB2 (0.49) PPARDPOLBTDP1CHRNB2CHRNA4
SCHEMBL6167829 0.74 ALOX15 (0.59) PPARDPOLBTDP1NQO1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265398-B1 INSECTICIDES, FUNGICIDES, ANTIFERTILITY AGENTS HOECHST SCHERING AGREVO GMBH (DE) 2001-07-24 US disclosed
EP-0898565-A1 SUBSTITUTED PYRIDINES/PYRIMIDINES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PEST CONTROL AGENTS Hoechst Schering AgrEvo GmbH (DE) 1999-03-03 EP disclosed
WO-1997038979-A1 SUBSTITUTED PYRIDINES/PYRIMIDINES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PEST CONTROL AGENTS HOECHST SCHERING AGREVO GMBH (DE) 1997-10-23 WO disclosed