Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816804 | 0.79 | ALDH1A1 (0.48) | RORCPOLBALOX15HTTMAPT | |
| SCHEMBL7947441 | 0.74 | SMN1; SMN2 (0.47) | POLBHTTMAPTKMT2AMEN1 | |
| SCHEMBL6816810 | 0.74 | RORC (0.41) | RORCPOLBALOX15HTTKMT2A | |
| SCHEMBL6810838 | 0.69 | RORC (0.61) | RORCMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7939224 | 0.66 | EPHX2 (0.39) | RORCHTTMAPTKMT2AMEN1 | |
| SCHEMBL7939052 | 0.66 | ALDH1A1 (0.49) | RORCHTTMAPTKMT2AMEN1 | |
| SCHEMBL7945326 | 0.66 | KMT2A (0.41) | POLBHTTMAPTKMT2AMEN1 | |
| SCHEMBL8794781 | 0.65 | CNR1 (0.55) | POLBHTTMAPTKMT2AMEN1 | |
| SCHEMBL6819660 | 0.65 | MAPT (0.55) | RORCPOLBHTTMAPTKMT2A | |
| SCHEMBL2019227 | 0.64 | LMNA (0.42) | POLBALOX15HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |