Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MB | P02144 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939140 | 0.79 | KMT2A (0.43) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7939128 | 0.74 | LMNA (0.52) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7948477 | 0.74 | RORC (0.40) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11431434 | 0.74 | LMNA (0.52) | SMN1; SMN2KMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL6816348 | 0.73 | ALDH1A1 (0.54) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8794781 | 0.72 | CNR1 (0.55) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7939052 | 0.71 | ALDH1A1 (0.49) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7945326 | 0.68 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13941263 | 0.68 | TSHR (0.58) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6816354 | 0.68 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |