SCHEMBL7948551

SCHEMBL7948551

Cc1ccc(OP(F)Oc2ccc(C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.36
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ACHE P22303 1/20 0.36
CA2 P00918 1/20 0.36
POLB P06746 1/20 0.36
TYR P14679 1/20 0.36
SYK P43405 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 3/20 0.33
CYP3A4 P08684 2/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 2/20 0.32
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.32
SCN9A Q15858 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7948553 0.86 SMN1; SMN2 (0.38) USP2ALDH1A1SMN1; SMN2ACHECA2
SCHEMBL132991 0.85 ALDH1A1 (0.39) USP2ALDH1A1SMN1; SMN2ACHECA2
SCHEMBL29367415 0.85 ALDH1A1 (0.39) USP2ALDH1A1SMN1; SMN2ACHECA2
SCHEMBL7942168 0.82 NR3C1 (0.37) SMN1; SMN2ACHECA2POLBSYK
SCHEMBL2332261 0.81 CA1 (0.39) ALDH1A1SMN1; SMN2CA2POLBMEN1
SCHEMBL5960888 0.81 USP2 (0.36) USP2ALDH1A1SMN1; SMN2ACHECA2
SCHEMBL2775176 0.81 ALDH1A1 (0.41) USP2ALDH1A1SMN1; SMN2ACHECA2
SCHEMBL11262011 0.81 ALDH1A1 (0.41) USP2ALDH1A1SMN1; SMN2ACHECA2
SCHEMBL9512886 0.80 CNR1 (0.35) ALDH1A1ACHESYKCYP3A4ALOX15
SCHEMBL7948556 0.80 USP2 (0.36) USP2ALDH1A1SMN1; SMN2ACHECA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36128-E STABILIZER FOR ORGANIC COMPOUNDS ALBEMARLE CORPORATION (US) 1999-03-02 US claimed
US-4912155-A Containing substituted aryl group ETHYL CORPORATION (US) 1990-03-27 US claimed
EP-0280938-A1 Antioxidant aromatic fluorophosphites ALBEMARLE CORPORATION (US) 1988-09-07 EP claimed
US-6231804-B1 USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER CHISSO CORPORATION (JP) 2001-05-15 US disclosed
EP-1017494-A1 HYDROFORMYLATION PROCESS USING NOVEL PHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 2000-07-12 EP disclosed
EP-0972800-A1 MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING CHISSO CORPORATION (JP) 2000-01-19 EP disclosed
WO-1999013984-A1 HYDROFORMYLATION PROCESS USING NOVEL PHOSPHITE-METAL CATALYST SYSTEM EASTMAN CHEMICAL COMPANY (US) 1999-03-25 WO disclosed