SCHEMBL7948892

SCHEMBL7948892

Cc1cc(OCC(C)Nc2nc(N)nc(C(C)(C)F)n2)ccc1F

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 5/20 0.36
ADRA1D P25100 2/20 0.36
ADRA1A P35348 2/20 0.36
ADRA1B P35368 2/20 0.36
HRH4 Q9H3N8 1/20 0.34
LMNA P02545 1/20 0.33
CARM1 Q86X55 1/20 0.32
KDM4E B2RXH2 2/20 0.32
NPC1 O15118 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
FFAR1 O14842 2/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
NR3C1 P04150 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3433358 0.92 HTR7 (0.39) HTR7ADRA1DADRA1AADRA1BHRH4
SCHEMBL9066422 0.84 DCPS (0.39) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL9240771 0.84 ADRB2 (0.40) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL117903 0.83 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL22188696 0.83 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL29352185 0.83 HTR7 (0.33) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL7116723 0.83 HTR7 (0.35) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL3433849 0.83 LMNA (0.40) HTR7ADRA1DADRA1AADRA1BLMNA
SCHEMBL3433363 0.83 HTR7 (0.36) HTR7ADRA1DADRA1AADRA1BHRH4
Bromomethane SCHEMBL3305907 0.81 HTR7 (0.32) HTR7ADRA1DADRA1AADRA1BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001043546-A2 COMBINATIONS OF HERBICIDAL ALKYLAZINES AND SAFENERS AVENTIS CROPSCIENCE GMBH (DE) 2001-06-21 WO disclosed