Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505929 | 0.91 | LTA4H (0.45) | ALOX5LTA4HLAP3MAOBPPARG | |
| SCHEMBL8390854 | 0.90 | ITGB3 (0.49) | LTA4HLAP3MAOBCA1CA2 | |
| SCHEMBL7510212 | 0.87 | CA1 (0.46) | LTA4HLAP3CA1CA2L3MBTL1 | |
| SCHEMBL7950553 | 0.78 | ALDH1A1 (0.44) | MAOBPPARGPPARA | |
| SCHEMBL7950550 | 0.78 | CA1 (0.41) | ALOX5LTA4HCA1CA2L3MBTL1 | |
| SCHEMBL339168 | 0.75 | ALDH1A1 (0.61) | CA1CA2L3MBTL1CA4LMNA | |
| SCHEMBL8581434 | 0.75 | ITGB3 (0.37) | LTA4HPPARGPPARALMNA | |
| SCHEMBL2438787 | 0.75 | LTA4H (0.60) | ALOX5LTA4HLAP3MAOBPPARG | |
| SCHEMBL8873994 | 0.74 | ITGB3 (0.37) | LTA4HMAOBPPARGPPARACA1 | |
| SCHEMBL27871586 | 0.74 | LTA4H (0.62) | ALOX5LTA4HLAP3MAOBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6254850-B1 | POLYCARBOXYALKYLAMINOALKANES FOR COMPLEXES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| US-6040432-A | Metal complexes, of DTPA derivatives suitable for use in diagnosis and therapy | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |
| EP-0810989-B1 | NOVELLY SUBSTITUTED DTPA DERIVATIVES, METAL COMPLEXES THEREOF, PHARMACEUTICALS CONTAINING THESE COMPLEXES, DIAGNOSTIC AND THERAPEUTIC USES THEREOF AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AG (DE) | 1999-08-04 | — | — | EP | disclosed |