Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 8/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505929 | 0.88 | LTA4H (0.45) | CA1CA2CA4LMNAMAPK1 | |
| SCHEMBL8390854 | 0.87 | ITGB3 (0.49) | CA1CA2CA4L3MBTL1LTA4H | |
| SCHEMBL7948959 | 0.87 | ALOX5 (0.46) | CA1CA2CA4LMNAL3MBTL1 | |
| SCHEMBL13535120 | 0.81 | LMNA (0.49) | CA4LMNACTRB1ALDH1A1MAPK1 | |
| SCHEMBL339168 | 0.80 | ALDH1A1 (0.61) | CA1CA2CA4LMNAALDH1A1 | |
| SCHEMBL7511620 | 0.76 | CTSS (0.40) | CA1CA2CA4CTSSCTSK | |
| SCHEMBL3093075 | 0.76 | CA1 (0.68) | CA1CA2CA4LMNAALDH1A1 | |
| SCHEMBL13589983 | 0.76 | CA1 (0.68) | CA1CA2CA4LMNAALDH1A1 | |
| SCHEMBL7950550 | 0.76 | CA1 (0.41) | CA1CA2CA4LMNAALDH1A1 | |
| SCHEMBL7438541 | 0.75 | CTRB1 (0.49) | LMNACTRB1ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170021-A2 | Conjugates of peptides and lanthanid-chelates for fluorescencediagnostic | Shering Aktiengesellschaft (DE) | 2002-01-09 | — | — | EP | disclosed |
| US-6254850-B1 | POLYCARBOXYALKYLAMINOALKANES FOR COMPLEXES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-07-03 | — | — | US | disclosed |
| EP-0810989-B1 | NOVELLY SUBSTITUTED DTPA DERIVATIVES, METAL COMPLEXES THEREOF, PHARMACEUTICALS CONTAINING THESE COMPLEXES, DIAGNOSTIC AND THERAPEUTIC USES THEREOF AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AG (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0775104-B1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AG (DE) | 1999-05-06 | — | — | EP | disclosed |