Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794992 | 0.90 | KCNH2 (0.46) | KCNH2MCHR1EPHX2P2RX7 | |
| SCHEMBL807608 | 0.90 | KCNH2 (0.46) | KCNH2MCHR1EPHX2P2RX7 | |
| SCHEMBL807583 | 0.88 | ALDH1A1 (0.38) | KCNH2MCHR1LMNAEPHX2NR1H4 | |
| SCHEMBL794562 | 0.84 | AR (0.31) | — | |
| SCHEMBL12467308 | 0.80 | TRPV1 (0.36) | KCNH2 | |
| SCHEMBL808171 | 0.79 | ALDH1A1 (0.37) | KCNH2MCHR1EPHX2NR1H4P2RX7 | |
| SCHEMBL12467058 | 0.79 | METAP2 (0.40) | KCNH2MCHR1LMNAEPHX2NR1H4 | |
| SCHEMBL17874618 | 0.77 | P2RX7 (0.37) | EPHX2P2RX7 | |
| SCHEMBL17874617 | 0.76 | AR (0.42) | KCNH2MCHR1EPHX2P2RX7 | |
| SCHEMBL15474190 | 0.76 | EPHX2 (0.35) | EPHX2NR1H4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | KCNH2 177/4885MCHR1 1165/4885LMNA 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.