Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949760 | 0.91 | TAS1R3 (0.44) | GPR88HTTRORCAKR1C3AKR1C2 | |
| SCHEMBL7960866 | 0.83 | SCN1A (0.41) | GPR88HTTRORCAKR1C3AKR1C2 | |
| SCHEMBL7950150 | 0.82 | AKR1C3 (0.40) | GPR88HTTAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7961960 | 0.82 | GPR88 (0.49) | GPR88AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL7961953 | 0.82 | GPR88 (0.37) | GPR88HTTAKR1C3AKR1C2PTGS1 | |
| SCHEMBL7964513 | 0.82 | LPAR1 (0.43) | GPR88 | |
| SCHEMBL6987357 | 0.81 | MEN1 (0.42) | HTTAKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL7960618 | 0.78 | SCN1A (0.41) | HTTRORCAKR1C3AKR1C2PTGS1 | |
| SCHEMBL7959909 | 0.78 | PTGS2 (0.37) | GPR88HTTAKR1C3AKR1C2PTGS1 | |
| SCHEMBL7961961 | 0.77 | MTNR1A (0.35) | GPR88HTTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |