Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689313 | 0.79 | EGLN1 (0.72) | EGLN1ALDH1A1KDR | |
| SCHEMBL7683260 | 0.76 | EGLN1 (0.71) | EGLN1POLBALDH1A1KDR | |
| SCHEMBL29395449 | 0.75 | POLB (0.63) | POLBALDH1A1MAPK8DPP4MKNK1 | |
| SCHEMBL7994938 | 0.74 | POLB (0.62) | POLBALDH1A1MAPK8DPP4MKNK1 | |
| SCHEMBL7684585 | 0.73 | RAB9A (0.56) | EGLN1ALDH1A1KDR | |
| SCHEMBL7690027 | 0.73 | EGLN1 (0.66) | EGLN1POLBALDH1A1KDR | |
| SCHEMBL7233175 | 0.73 | GAA (0.65) | POLBALDH1A1MAPK8DPP4 | |
| SCHEMBL7692718 | 0.73 | KCNMA1 (0.59) | EGLN1POLBALDH1A1KDR | |
| SCHEMBL6697154 | 0.72 | ALDH1A1 (0.63) | POLBALDH1A1MAPK8DPP4MKNK1 | |
| SCHEMBL13947445 | 0.72 | POLB (0.60) | POLBALDH1A1MAPK8DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | claimed |
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |