Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | METAP2 | P50579 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159826 | 0.88 | MEN1 (0.60) | HTTSMN1; SMN2HPGDALDH1A1GAA | |
| SCHEMBL4958960 | 0.86 | ALDH1A1 (0.77) | HTTSMN1; SMN2ALDH1A1GAANCOA1 | |
| SCHEMBL8711203 | 0.85 | RAB9A (0.74) | HTTSMN1; SMN2ALDH1A1GAANPC1 | |
| SCHEMBL5222691 | 0.84 | ALDH1A1 (0.70) | HTTSMN1; SMN2HPGDALDH1A1GAA | |
| Methyl Alcohol SCHEMBL4957272 | 0.84 | GAA (0.73) | HTTSMN1; SMN2ALDH1A1GAANCOA1 | |
| SCHEMBL995085 | 0.84 | GAA (0.77) | HTTSMN1; SMN2ALDH1A1GAANCOA1 | |
| SCHEMBL5223546 | 0.83 | NPC1 (0.59) | HTTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5226429 | 0.83 | RAB9A (0.78) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL2309322 | 0.83 | KMT2A (0.73) | ALDH1A1NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL94829 | 0.82 | GAA (0.71) | HTTSMN1; SMN2ALDH1A1GAANCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646908-B | Method for preparing aromatic amine compound | 宜昌尚诺德生物医药科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-111732493-B | Synthesis process of arylamine compound | 宜昌尚诺德生物医药科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-111732493-A | Synthesis process of arylamine compound | 宜昌尚诺德生物医药科技有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-111646908-A | Method for preparing aromatic amine compound | 宜昌尚诺德生物医药科技有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-106800493-B | Method for reducing aromatic nitro group into aromatic amine | 宜昌尚诺德生物医药科技有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-106800493-A | Method for reducing aromatic nitro group into aromatic amine | 三峡大学 | 2017-06-06 | — | — | CN | disclosed |
| EP-1963276-B9 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2012-09-26 | — | — | EP | disclosed |
| EP-1963276-B1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2012-06-20 | — | — | EP | disclosed |
| US-7674802-B2 | leukotriene A4 hydrolase inhibitors; biaryl nitrogen-attached heterocycles | DECODE GENETICS, EHF (IS) | 2010-03-09 | — | — | US | disclosed |
| US-7674802-B2 | leukotriene A4 hydrolase inhibitors; biaryl nitrogen-attached heterocycles | DECODE GENETICS, EHF (IS) | 2010-03-09 | — | — | US | disclosed |
| EP-1963276-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | Decode Genetics EHF (IS) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007073405-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2007-06-28 | — | — | WO | disclosed |
| US-20070142434-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE CHEMISTRY, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070142434-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE CHEMISTRY, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-4123554-A | Fungicidal and germicidal benzanilides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1978-10-31 | — | — | US | disclosed |
| US-3985804-A | Agricultural substituted 2-methylbenzanilide germicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
| US-3937840-A | COMPOSITIONS AND METHODS OF COMBATTING BACTERIA AND FUNGI USING 2-METHYLBENZANILIDE DERIVATIVES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142434-A1 | N-LINKED ARYL HETEROARYL INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | LTA4H, LTB4R, LTC4S | HTT 2529/4885SMN1; SMN2 4852/4885HPGD 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.