Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950420 | 0.87 | DRD2 (0.54) | DRD2DRD1DRD4DRD3HTR1A | |
| SCHEMBL7930304 | 0.80 | DRD2 (0.48) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| SCHEMBL30580523 | 0.78 | DRD2 (0.63) | DRD2DRD1DRD4DRD3HTR1A | |
| SCHEMBL7785750 | 0.75 | DRD2 (0.70) | DRD2DRD1DRD4DRD3HTR1A | |
| SCHEMBL7785753 | 0.75 | DRD2 (0.70) | DRD2DRD1DRD4DRD3HTR1A | |
| SCHEMBL7933904 | 0.74 | DRD2 (0.43) | DRD2DRD1ADRA1DADRA1AADRA1B | |
| SCHEMBL8218482 | 0.74 | NFKB1 (0.34) | — | |
| SCHEMBL15285331 | 0.73 | CA14 (0.36) | — | |
| SCHEMBL22005149 | 0.73 | DRD2 (0.47) | DRD2DRD1DRD4DRD3HTR1A | |
| SCHEMBL339878 | 0.72 | DRD2 (0.53) | DRD2DRD1DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009156458-A1 | NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF | H. LUNDBECK A/S (DK) | 2009-12-30 | — | — | WO | disclosed |