Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7951045 | 0.99 | APAF1 (0.33) | DRD2DRD4APAF1TDP2NSD2 | |
| Hydrochloric Acid SCHEMBL7949132 | 0.78 | NPC1 (0.38) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7951023 | 0.77 | DRD2 (0.32) | DRD2DRD4APAF1TDP2NSD2 | |
| Hydrochloric Acid SCHEMBL7952814 | 0.76 | CYP2C19 (0.39) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7949119 | 0.74 | APAF1 (0.35) | APAF1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7950487 | 0.74 | GAA (0.30) | — | |
| Hydrochloric Acid SCHEMBL7950423 | 0.74 | GPR3 (0.31) | — | |
| SCHEMBL7950407 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6388088 | 0.70 | DRD2 (0.32) | DRD2DRD4APAF1TDP2NSD2 | |
| Hydrochloric Acid SCHEMBL7950405 | 0.70 | PTPN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | claimed |