SCHEMBL7953400

SCHEMBL7953400

CC(=Cc1ccccc1C)N(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
TSHR P16473 3/20 0.41
TRPM8 Q7Z2W7 4/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
NPSR1 Q6W5P4 3/20 0.38
KDM4E B2RXH2 1/20 0.35
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
RAB9A P51151 2/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
THPO P40225 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379140 0.76 TRPM8 (0.50) ALDH1A1TSHRTRPM8KMT2AMEN1
SCHEMBL379142 0.76 TRPM8 (0.50) ALDH1A1TSHRTRPM8KMT2AMEN1
SCHEMBL29293295 0.74 ALDH1A1 (0.48) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL14864730 0.74 ALDH1A1 (0.48) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL257719 0.73 ALDH1A1 (0.52) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL18745271 0.73 NPSR1 (0.48) ALDH1A1TSHRTRPM8KMT2AMEN1
SCHEMBL842429 0.71 TSHR (0.45) ALDH1A1TSHRNPSR1KDM4EMAPT
SCHEMBL17011300 0.70 ALDH1A1 (0.34) ALDH1A1TSHRKMT2AMEN1NPSR1
SCHEMBL14950437 0.70 ALDH1A1 (0.48) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL13891036 0.70 ALDH1A1 (0.48) ALDH1A1TSHRKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001096416-A2 ETHYLENE/(METH)ACRYLATE COPOLYMERS HAVING AROMATIC AMINES GRAFTED THERETO UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-12-20 WO disclosed
EP-0734432-A1 SYNTHETIC ESTER LUBRICANT STABILIZER COMPOSITION GOODRICH CO B F (US) 1996-10-02 EP disclosed
WO-1995016765-A9 SYNTHETIC ESTER LUBRICANT STABILIZER COMPOSITION 1995-08-24 WO disclosed
WO-1995016765-A2 SYNTHETIC ESTER LUBRICANT STABILIZER COMPOSITION THE B.F. GOODRICH COMPANY (US) 1995-06-22 WO disclosed