Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891036 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL7188617 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL257719 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDLMNAHTT | |
| Hydrochloric Acid SCHEMBL5143701 | 0.81 | TRPA1 (0.40) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL25109162 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL4744668 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL23130300 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL14864730 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL22478581 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRHPGDLMNAHTT | |
| SCHEMBL29128997 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRHPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2016-12-08 | — | — | US | disclosed |
| US-9439436-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160228437-A1 | MIXED LINEAGE KINASE INHIBITORS AND METHOD OF TREATMENTS | Califia Bio, Inc. | 2016-08-11 | — | — | US | disclosed |
| US-20160206614-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. | 2016-07-21 | — | — | US | disclosed |
| US-9370515-B2 | Mixed lineage kinase inhibitors and method of treatments | Califia Bio, Inc. (US) | 2016-06-21 | — | — | US | disclosed |
| US-9290453-B2 | Quinolines and aza-quinolines as CRTH2 receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150327552-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | UNIV NORTH CAROLINA STATE (US) | 2015-11-19 | — | — | US | disclosed |
| US-9125408-B2 | Use of aryl carbamates in agriculture and other plant-related areas | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-09-08 | — | — | US | disclosed |
| US-9018210-B2 | Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-8884022-B2 | Inhibition of bacterial biofilms with aryl carbamates | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-11-11 | — | — | US | disclosed |
| US-20140302069-A1 | MODULATORS OF C3A RECEPTORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2014-10-09 | — | — | US | disclosed |
| US-20130296300-A1 | QUINOLINES AND AZA-QUINOLINES AS CRTH2 RECEPTOR MODULATORS | MERCK SHARP & DOHME LLC | 2013-11-07 | — | — | US | disclosed |
| US-20130190315-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | NORTH CAROLINA STATE UNIVERSITY | 2013-07-04 | — | — | US | disclosed |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172187-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | ALDH1A1 2905/4885TSHR 639/4885HPGD 4557/4885 |
| US-20160353739-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | ALDH1A1 2905/4885TSHR 639/4885HPGD 4557/4885 |
| US-20130123225-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | PGLS, BLVRB, AADAC | ALDH1A1 3261/4885TSHR 2075/4885HPGD 3129/4885 |
| US-20160228437-A1 | MIXED LINEAGE KINASE INHIBITORS AND METHOD OF TREATMENTS | MAP3K2, MAP3K1, MAP3K20 | ALDH1A1 3770/4885TSHR 3439/4885HPGD 3192/4885 |
| US-20140302069-A1 | MODULATORS OF C3A RECEPTORS | C3AR1, C5AR2, C5AR1 | ALDH1A1 3274/4885TSHR 272/4885HPGD 1700/4885 |
| US-20160206614-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | HBB, HBG2, MB | ALDH1A1 216/4885TSHR 3012/4885HPGD 202/4885 |
| US-20150327552-A1 | USE OF ARYL CARBAMATES IN AGRICULTURE AND OTHER PLANT-RELATED AREAS | CTRC, ACE, DDT | ALDH1A1 2905/4885TSHR 639/4885HPGD 4557/4885 |
| US-20130190315-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | HBB, HBG2, MB | ALDH1A1 216/4885TSHR 3012/4885HPGD 202/4885 |
| US-20130296300-A1 | QUINOLINES AND AZA-QUINOLINES AS CRTH2 RECEPTOR MODULATORS | HRH2, NPY2R, CNKSR1 | ALDH1A1 1882/4885TSHR 173/4885HPGD 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.