SCHEMBL7954444

SCHEMBL7954444

C=CC(=O)OCCOC(=O)NCC

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.55
ALDH1A1 P00352 3/20 0.55
TP53 P04637 2/20 0.55
HIF1A Q16665 2/20 0.55
HSD17B10 Q99714 1/20 0.55
HPGD P15428 1/20 0.55
THRB P10828 2/20 0.50
CYP3A4 P08684 1/20 0.50
CHRNB2 P17787 1/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
CHRNA4 P43681 1/20 0.46
ACHE P22303 7/20 0.46
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19010224 0.95 TSHR (0.66) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL16380406 0.93 TSHR (0.62) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL13032934 0.85 ACHE (0.56) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10822205 0.85 TSHR (0.46) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL5943029 0.84 TSHR (0.59) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL18353144 0.84 CHRNB2 (0.53) CHRNB2CHRNB4CHRNA3CHRNA4ACHE
SCHEMBL16674069 0.83 ACHE (0.60) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL22196862 0.83 ACHE (0.50) TSHRALDH1A1HPGDCYP3A4ACHE
SCHEMBL13872046 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL12111976 0.82 TSHR (0.57) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12091866-B2 Water resistant wood flooring AHF, LLC (US) 2024-09-17 US disclosed
EP-3523386-B1 FLOOR COATINGS COMPRISING A RESIN, A CURE SYSTEM AND DIAMOND PARTICLES AND METHODS OF MAKING THE SAME AHF LLC D/B/A AHF PRODUCTS (US) 2024-06-12 EP disclosed
US-11786444-B2 Dental polyfunctional monomers and dental hydroxyl group-containing monomers MITSUI CHEMICALS, INC. (JP) 2023-10-17 US disclosed
WO-2023160710-A1 RESIN, METHOD FOR PREPARING RESIN, AND USE OF RESIN 华为技术有限公司 2023-08-31 WO disclosed
US-20230102660-A1 WATER RESISTANT WOOD FLOORING UBS AG, STAMFORD BRANCH 2023-03-30 US disclosed
US-11548962-B2 Self-healing polymer network containing physical crosslinker, composition therefor, and optical element comprising the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2023-01-10 US disclosed
US-11492810-B2 Water resistant wood flooring AHF, LLC (US) 2022-11-08 US disclosed
WO-2022104113-A1 SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2022-05-19 WO disclosed
US-11311357-B2 Dental composite material and mill blanks consisting of said composite material KULZER GMBH (DE) 2022-04-26 US disclosed
EP-3374580-B1 SURFACE COVERING HAVING AN IMPROVED WEAR LAYER AFI LICENSING LLC (US) 2022-02-23 EP disclosed
US-20100076115-A1 Compositions For Dental Composites With Tricyclo[5.2.1.02.6]decane Derivatives HERAEUS KULZER GMBH (DE) 2010-03-25 US disclosed
US-20070060665-A1 polymerization initiator and a monofunctional (meth)acrylate having a CONH bond in the molecule; acrylate monomer having an amide or carbamate or urea in the side chain; hydrogen bonding increases curing speed and flexibility of film FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-20070060665-A1 polymerization initiator and a monofunctional (meth)acrylate having a CONH bond in the molecule; acrylate monomer having an amide or carbamate or urea in the side chain; hydrogen bonding increases curing speed and flexibility of film FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-6258441-B1 PHOTOPOLYMERIZATION; ACRYLATED POLYURETHANE DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 2001-07-10 US disclosed
US-5401348-A Wear and imapct resistant DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1995-03-28 US disclosed
US-4618635-A RADIATION CURABLE; HIGH TENSILE STRENGTH UNION CARBIDE CORPORATION (US) 1986-10-21 US disclosed
EP-0133908-A2 Compositions useful in curable coatings UNION CARBIDE CORPORATION (US) 1985-03-13 EP disclosed
US-4165266-A LIQUID MONOACRYLATE MONOMER AND A POLYVINYL ALKYL ETHER, QUICK STICKING UNION CARBIDE CORPORATION (US) 1979-08-21 US disclosed
US-4143013-A ACRYLIC FUNCTIONAL OLIGOMER; ORTHOSILICATES AS DILUENTS UNION CARBIDE CORPORATION (US) 1979-03-06 US disclosed
US-4131602-A Radiation curable acrylated polyurethane UNION CARBIDE CORPORATION (US) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076115-A1 Compositions For Dental Composites With Tricyclo[5.2.1.02.6]decane Derivatives DCTD, CDA, XPA TSHR 2370/4885ALDH1A1 1133/4885TP53 449/4885
US-11786444-B2 Dental polyfunctional monomers and dental hydroxyl group-containing monomers PAM, CAD, FHIT TSHR 2948/4885ALDH1A1 1173/4885TP53 2612/4885
US-11311357-B2 Dental composite material and mill blanks consisting of said composite material CAD, PUF60, MSH2 TSHR 2706/4885ALDH1A1 2347/4885TP53 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.