Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BRS3 | P32247 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954954 | 0.80 | OPRK1 (0.42) | KDM4ENPC1GAAMEN1KMT2A | |
| SCHEMBL29790470 | 0.75 | PPARA (0.54) | POLBALDH1A1PPARA | |
| SCHEMBL7954472 | 0.74 | UTS2R (0.48) | — | |
| SCHEMBL8308100 | 0.73 | TACR1 (0.61) | — | |
| SCHEMBL8807008 | 0.72 | MEN1 (0.42) | POLBALDH1A1KDM4EGAALMNA | |
| SCHEMBL7947193 | 0.68 | HRH1 (0.56) | — | |
| SCHEMBL9027580 | 0.68 | TACR2 (0.49) | — | |
| SCHEMBL25139677 | 0.66 | ALDH1A1 (0.59) | POLBL3MBTL1ALDH1A1KDM4ERAB9A | |
| SCHEMBL12384538 | 0.66 | ALDH1A1 (0.59) | POLBL3MBTL1ALDH1A1KDM4ERAB9A | |
| SCHEMBL13826659 | 0.66 | SIGMAR1 (0.60) | POLBL3MBTL1ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |