Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794810 | 0.75 | MEN1 (0.38) | ALDH1A1L3MBTL1TP53ALOX12MAPK1 | |
| SCHEMBL3938152 | 0.69 | NPC1 (0.38) | ALDH1A1L3MBTL1MAPK1NOTUMKMT2A | |
| SCHEMBL729042 | 0.63 | KDM4E (0.41) | ALDH1A1SHMT2L3MBTL1TP53MAPK1 | |
| SCHEMBL794740 | 0.63 | LMNA (0.39) | ALDH1A1SHMT2L3MBTL1TP53MAPK1 | |
| SCHEMBL4407303 | 0.60 | HPGD (0.57) | ALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL3777938 | 0.60 | NOTUM (0.68) | L3MBTL1NOTUMMAOA | |
| SCHEMBL156901 | 0.60 | HTT (0.60) | ALDH1A1L3MBTL1MEN1KMT2ATSHR | |
| Bromide SCHEMBL1882333 | 0.59 | NOTUM (0.66) | L3MBTL1NOTUMMAOA | |
| SCHEMBL796343 | 0.59 | ALDH1A1 (0.35) | ALDH1A1SHMT2L3MBTL1TP53MAPK1 | |
| SCHEMBL8621188 | 0.58 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1TP53ALOX12MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | BASF SE (DE) | 2019-02-19 | — | — | US | disclosed |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| EP-2616458-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2013-08-08 | — | — | US | disclosed |
| EP-2616458-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034960-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | PRXL2A, NR2C2, SHROOM3 | ALDH1A1 1345/4885SHMT2 1384/4885L3MBTL1 2367/4885 |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | PRXL2A, SHROOM3, NR2C2 | ALDH1A1 1331/4885SHMT2 1417/4885L3MBTL1 2339/4885 |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | GRIN2A, NR2C2, GRIA2 | ALDH1A1 1480/4885SHMT2 700/4885L3MBTL1 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.