Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354007 | 0.75 | KDM4E (0.45) | KDM4EHPGDP2RX7ALDH1A1MAPK1 | |
| SCHEMBL29483355 | 0.70 | KDM4E (0.54) | KDM4EHPGDP2RX7ALDH1A1MAPK1 | |
| SCHEMBL12713296 | 0.64 | KDM4E (0.49) | KDM4EHPGDALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4407303 | 0.64 | HPGD (0.57) | KDM4EHPGDALDH1A1ADORA1LMNA | |
| SCHEMBL12146363 | 0.64 | P2RX7 (0.68) | KDM4EHPGDP2RX7ALDH1A1MAPK1 | |
| SCHEMBL795459 | 0.63 | ALDH1A1 (0.37) | HPGDALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL7148312 | 0.63 | SMN1; SMN2 (0.49) | KDM4EHPGDP2RX7ALDH1A1MAPK1 | |
| SCHEMBL416916 | 0.62 | KDM4E (0.61) | KDM4EHPGDALDH1A1MAPK1ADORA1 | |
| SCHEMBL6312839 | 0.61 | ALDH1A1 (0.64) | KDM4EHPGDALDH1A1MAPK1ADORA1 | |
| SCHEMBL11861466 | 0.61 | KDM4E (0.67) | KDM4EHPGDP2RX7ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178523-A1 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-08-10 | — | — | US | claimed |
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | BASF SE (DE) | 2019-02-19 | — | — | US | disclosed |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2018-05-03 | — | — | US | disclosed |
| EP-2616458-B1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | BASF SE (DE) | 2013-08-08 | — | — | US | disclosed |
| EP-2616458-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| CN-103097376-A | Pyridine compounds for controlling invertebrate pests ii | BASF SE | 2013-05-08 | — | — | CN | disclosed |
| US-8324420-B2 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| WO-2012034960-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS II | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| US-8138368-B2 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20110313173-A1 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-12-22 | — | — | US | disclosed |
| US-20100029951-A1 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7649104-B2 | producing 3-acyloxyacrylonitrile compound as an agricultural and horticultural pesticide; using the produced 3-oxopropionitrile compound as the intermediate | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20060178523-A1 | Process for producing acrylonitrile compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10206401-B2 | Pyridine compounds for controlling invertebrate pests II | PRXL2A, NR2C2, SHROOM3 | KDM4E 2131/4885HPGD 2559/4885P2RX7 1026/4885 |
| US-20180116221-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | PRXL2A, SHROOM3, NR2C2 | KDM4E 2158/4885HPGD 2415/4885P2RX7 871/4885 |
| US-20130203821-A1 | Pyridine Compounds for Controlling Invertebrate Pests II | GRIN2A, NR2C2, GRIA2 | KDM4E 2495/4885HPGD 2129/4885P2RX7 978/4885 |
| US-20060178523-A1 | Process for producing acrylonitrile compound | ZYX, ACR, ZDHHC9 | KDM4E 1437/4885HPGD 2895/4885P2RX7 4054/4885 |
| US-20110313173-A1 | Process for producing acrylonitrile compound | ZYX, ACR, ZDHHC9 | KDM4E 1437/4885HPGD 2895/4885P2RX7 4054/4885 |
| US-20100029951-A1 | Process for producing acrylonitrile compound | ZYX, ACR, ZDHHC9 | KDM4E 1437/4885HPGD 2895/4885P2RX7 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.