Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BAX | Q07812 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104753 | 0.86 | LTA4H (0.35) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL2522708 | 0.84 | LTA4H (0.41) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL9601104 | 0.80 | LTA4H (0.38) | LTA4HTSHRCA5ACA5BCA4 | |
| Potassium Ion SCHEMBL28444151 | 0.78 | CA12 (0.47) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL8731765 | 0.74 | ALOX15 (0.44) | LTA4HTSHRCA5ACA5BSRC | |
| SCHEMBL4592607 | 0.74 | ALOX15 (0.44) | LTA4HTSHRCA5ACA5BALDH1A1 | |
| SCHEMBL14905 | 0.73 | LTA4H (0.60) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL2470101 | 0.72 | LTA4H (0.45) | LTA4HTSHRCA5ACA5BCA4 | |
| SCHEMBL4466865 | 0.72 | ALOX15 (0.43) | LTA4HTSHRCA5ACA5BSRC | |
| Methyl Alcohol SCHEMBL28285968 | 0.71 | CA4 (0.53) | LTA4HTSHRCA5ACA5BCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177457-B1 | CYCLIZATION OF CHEMICAL INTERMEDIATES; FUNGICIDES | GLAXO WELLCOME S.A. (ES) | 2001-01-23 | — | — | US | disclosed |
| EP-0901493-A1 | PROCESS FOR THE PREPARATION OF AN INDACENE COMPOUND | Glaxo Wellcome S.A. (ES) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997042195-A1 | PROCESS FOR THE PREPARATION OF AN INDACENE COMPOUND | GLAXO WELLCOME S.A. (ES) | 1997-11-13 | — | — | WO | disclosed |