Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954828 | 0.78 | LTA4H (0.41) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL2522708 | 0.78 | LTA4H (0.41) | CA12CA1CA2CA9LTA4H | |
| Potassium Ion SCHEMBL11750983 | 0.76 | CA12 (0.48) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL9601104 | 0.74 | LTA4H (0.38) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL28493996 | 0.71 | CA12 (0.43) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL10423952 | 0.71 | CA12 (0.43) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL11452423 | 0.71 | CA12 (0.43) | CA12CA1CA2CA9LTA4H | |
| SCHEMBL8104753 | 0.71 | LTA4H (0.35) | LTA4HTSHRCA5ACA5BNR1H2 | |
| SCHEMBL4592607 | 0.69 | ALOX15 (0.44) | LTA4HTSHRCA5ACA5BALDH1A1 | |
| SCHEMBL8731765 | 0.69 | ALOX15 (0.44) | LTA4HTSHRCA5ACA5BSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138578-B | Hyperbranched polyvinyl acetate and high-stability writing ink based on same | 苏州雄鹰笔墨新材料有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-111138578-A | Hyperbranched polyvinyl acetate and high-stability writing ink based on same | 苏州雄鹰笔墨新材料有限公司 | 2020-05-12 | — | — | CN | disclosed |