Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 4/20 | 0.50 |
| ▸ | MMP13 | P45452 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936984 | 0.90 | MAOA (0.50) | MAOAMAOBTAAR1CYP1A2CYP2D6 | |
| SCHEMBL28113384 | 0.88 | MAOA (0.48) | MAOAMAOBTAAR1CYP1A2CYP2D6 | |
| SCHEMBL8763914 | 0.85 | MAOA (0.39) | MAOAMAOBKCNH2TSHRIDO1 | |
| SCHEMBL7829483 | 0.85 | MMP12 (0.44) | MMP12MMP13FFAR1MMEACE | |
| SCHEMBL9751807 | 0.80 | NOS1 (0.47) | MAOAMAOB | |
| SCHEMBL8762349 | 0.79 | MAOA (0.36) | MAOAMAOBKCNH2FAAHTSHR | |
| SCHEMBL9751809 | 0.78 | MIF (0.47) | MAOAMAOB | |
| SCHEMBL18792621 | 0.77 | NAAA (0.49) | MAOAMAOB | |
| SCHEMBL18792583 | 0.77 | NAAA (0.49) | MAOAMAOB | |
| SCHEMBL5551465 | 0.76 | FFAR1 (0.60) | MMP12MMP13FFAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329389-B1 | HETEROCYCLIC AMINES AND DERIVATIVES, SOMATOSTATIN AND ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |