Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MIF | P14174 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751809 | 0.94 | MIF (0.47) | MAOAMAOBMIFSIGMAR1NAAA | |
| SCHEMBL18792583 | 0.92 | NAAA (0.49) | MAOAMAOBMIFSIGMAR1NAAA | |
| SCHEMBL18792621 | 0.92 | NAAA (0.49) | MAOAMAOBMIFSIGMAR1NAAA | |
| SCHEMBL2936984 | 0.89 | MAOA (0.50) | NOS1MAOAMAOBMIFCA2 | |
| SCHEMBL28113384 | 0.87 | MAOA (0.48) | NOS1MAOAMAOBMIFCA2 | |
| SCHEMBL7955538 | 0.80 | MMP12 (0.50) | MAOAMAOB | |
| SCHEMBL8763914 | 0.80 | MAOA (0.39) | NOS1MAOAMAOBMIF | |
| SCHEMBL18784395 | 0.76 | TSHR (0.47) | MAOAMAOBCA2NAAA | |
| SCHEMBL779766 | 0.75 | NOS1 (0.55) | NOS1MAOAMAOBCA2SIGMAR1 | |
| SCHEMBL577035 | 0.75 | CA2 (0.62) | NOS1MAOAMAOBCA2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436005-A1 | LABELED POLYPEPTIDE DERIVATIVES. | SANDOZ LTD (CH) | 1991-07-10 | — | — | EP | claimed |
| JP-56095106-A | — | — | None | — | — | JP | disclosed |
| JP-S5695106-A | INJURIOUS INSECT REPELLENT | EARTH CHEM CORP LTD | 1981-08-01 | — | — | JP | disclosed |