Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 6/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711219 | 0.79 | DRD2 (0.48) | CHRM4DRD2DRD4DRD3KCNA3 | |
| SCHEMBL24986986 | 0.79 | CKS1B (0.56) | CHRM4DRD2ADAM17DRD4DRD3 | |
| SCHEMBL2464322 | 0.77 | KCNA3 (0.57) | DRD2KDM1ADRD3KCNA3 | |
| SCHEMBL7955964 | 0.76 | KDM1A (0.43) | NPY2RCHRM4DRD2ADAM17KDM1A | |
| SCHEMBL20139850 | 0.75 | KCNMA1 (0.50) | CHRM4DRD2DRD4DRD3 | |
| SCHEMBL12835989 | 0.75 | PIM1 (0.58) | DRD2DRD3KCNA3 | |
| SCHEMBL20149778 | 0.73 | DRD4 (0.43) | NPY2RCHRM4DRD2KDM1ADRD4 | |
| SCHEMBL31042542 | 0.72 | DRD4 (0.45) | CHRM4DRD2DRD4DRD3KDM4E | |
| SCHEMBL7523188 | 0.72 | HPGD (0.58) | KDM4EPKM | |
| SCHEMBL7715922 | 0.72 | DRD4 (0.47) | CHRM4DRD2DRD4DRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214832-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-04-10 | — | — | US | disclosed |