Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956692 | 0.84 | FPR2 (0.47) | HRH3GPR119CHKA | |
| SCHEMBL7958355 | 0.84 | HRH3 (0.42) | HRH3HCRTR1HCRTR2CHKAOXTR | |
| SCHEMBL7961541 | 0.81 | LIPG (0.53) | HRH3GPR119 | |
| SCHEMBL7956260 | 0.81 | DPP4 (0.47) | HRH3GPR119 | |
| SCHEMBL13432215 | 0.80 | TDO2 (0.50) | HRH3HCRTR1HCRTR2 | |
| SCHEMBL20261372 | 0.79 | HCRTR1 (0.44) | HRH3HCRTR1HCRTR2GPR119ACACB | |
| SCHEMBL7961706 | 0.79 | MAPT (0.46) | HRH3 | |
| SCHEMBL13432144 | 0.77 | HRH3 (0.52) | HRH3HCRTR1HCRTR2 | |
| SCHEMBL5632542 | 0.76 | ACACB (0.43) | HRH3OXTRAVPR1AACACB | |
| SCHEMBL7961553 | 0.76 | ACACB (0.41) | HRH3HCRTR1HCRTR2OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |