Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.48 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956714 | 0.88 | ACACB (0.60) | ACACBF10MCHR1FFAR4 | |
| SCHEMBL7954806 | 0.81 | ACACB (0.38) | ACACBF10OXTRAVPR1AFFAR4 | |
| SCHEMBL7961303 | 0.81 | F10 (0.54) | ACACBF10MCHR1FFAR4 | |
| SCHEMBL7957015 | 0.77 | ACACB (0.41) | ACACBOXTRAVPR1A | |
| SCHEMBL7947301 | 0.77 | ACACB (0.41) | ACACBOXTRAVPR1A | |
| SCHEMBL5632542 | 0.77 | ACACB (0.43) | ACACBOXTRAVPR1A | |
| SCHEMBL7961553 | 0.77 | ACACB (0.41) | ACACBOXTRAVPR1A | |
| SCHEMBL7954744 | 0.77 | FPR2 (0.43) | ACACBF10 | |
| SCHEMBL7955313 | 0.74 | ACACB (0.49) | ACACBFFAR4 | |
| SCHEMBL7956252 | 0.74 | LIPG (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |