Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 9/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957634 | 0.87 | ALDH1A1 (0.50) | DRD2CACNA1GDRD4DRD3ALDH1A1 | |
| SCHEMBL7961177 | 0.83 | OPRL1 (0.44) | DRD2OPRL1CCR2 | |
| SCHEMBL7964065 | 0.82 | DRD2 (0.53) | DRD2DRD4DRD3CCR2 | |
| SCHEMBL7949583 | 0.82 | DRD2 (0.54) | DRD2CACNA1GDRD4DRD3ALDH1A1 | |
| SCHEMBL7960163 | 0.81 | DRD2 (0.62) | DRD2DRD4DRD3CCR2 | |
| SCHEMBL7957636 | 0.81 | NPY1R (0.47) | DRD2OPRL1DRD4DRD3ALDH1A1 | |
| SCHEMBL7963815 | 0.80 | DRD2 (0.50) | DRD2DRD4DRD3CCR2 | |
| SCHEMBL7949576 | 0.80 | DRD2 (0.48) | DRD2CACNA1GDRD4DRD3ALDH1A1 | |
| SCHEMBL7957585 | 0.79 | KMT2A (0.48) | DRD2CACNA1GOPRL1CCR2POLB | |
| SCHEMBL7959651 | 0.78 | ALDH1A1 (0.43) | DRD2DRD4DRD3ALDH1A1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |