Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969211 | 0.91 | CPA1 (0.42) | CPA1FTOKDM4EALDH1A1LMNA | |
| SCHEMBL7973949 | 0.91 | FTO (0.42) | CPA1FTOKDM4EALDH1A1LMNA | |
| SCHEMBL7968421 | 0.68 | CPA1 (0.40) | CPA1KDM4EALDH1A1SMN1; SMN2KDM4C | |
| SCHEMBL7971542 | 0.67 | CPA1 (0.39) | CPA1KDM4EALDH1A1LMNAFNTA | |
| SCHEMBL6154631 | 0.63 | DHODH (0.77) | KDM4EALDH1A1LMNASMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL8763128 | 0.63 | CPA1 (0.97) | CPA1CPB2CPB1 | |
| SCHEMBL18912253 | 0.62 | NPC1 (0.66) | FTOALDH1A1SMN1; SMN2KDM4C | |
| SCHEMBL8764039 | 0.62 | CPA1 (0.72) | CPA1CPB2CPB1 | |
| SCHEMBL6853270 | 0.61 | CXCR2 (0.77) | KDM4EALDH1A1LMNASMN1; SMN2CXCR2 | |
| SCHEMBL11498895 | 0.61 | ALDH1A1 (0.77) | KDM4EALDH1A1KDM4CKDM5BHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |