Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954887 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL9212633 | 0.75 | HTR3A (0.66) | — | |
| SCHEMBL991263 | 0.74 | HRH1 (0.73) | KDM4EHRH1KCNH2 | |
| SCHEMBL6598243 | 0.74 | HTR3A (0.61) | — | |
| SCHEMBL6151147 | 0.74 | MEN1 (0.58) | KDM4EALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL7463700 | 0.74 | HTR3A (0.63) | HRH1LMNARAB9AKCNH2 | |
| Hydrochloric Acid SCHEMBL28374789 | 0.74 | HRH1 (0.72) | KDM4EHRH1KCNH2 | |
| Hydrochloric Acid SCHEMBL21815483 | 0.74 | HRH1 (0.72) | KDM4EHRH1KCNH2 | |
| SCHEMBL6597271 | 0.73 | KDM4E (0.66) | KDM4EALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL7954906 | 0.73 | HRH1 (0.52) | KDM4EALDH1A1HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |