Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 6/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992547 | 0.81 | HRH1 (0.66) | KDM4EHRH1ALDH1A1 | |
| SCHEMBL7958499 | 0.79 | KDM4E (0.52) | KDM4EHRH1ALDH1A1MEN1TSHR | |
| SCHEMBL9260913 | 0.79 | HRH1 (0.51) | KDM4EHRH1 | |
| SCHEMBL742529 | 0.77 | CNR2 (0.40) | KDM4ECCR5ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6619420 | 0.72 | BACE1 (0.49) | TSHR | |
| SCHEMBL3491256 | 0.72 | CCR5 (0.44) | CCR5TSHR | |
| SCHEMBL3489753 | 0.71 | CCR5 (0.43) | CCR5TSHR | |
| SCHEMBL19924890 | 0.70 | HRH1 (0.74) | KDM4EHRH1 | |
| SCHEMBL7629372 | 0.70 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL7203937 | 0.70 | CYP11B2 (0.46) | CCR5MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |