SCHEMBL7958557

SCHEMBL7958557

Cc1cc(C)c([CH]c2cncc(Cl)c2)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAF1 P04049 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
PKMYT1 Q99640 1/20 0.31
RAPGEF4 Q8WZA2 3/20 0.31
PTGS2 P35354 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969830 0.72 TP53 (0.43) MEN1KMT2APTGS2
SCHEMBL7968526 0.70 LMNA (0.40) KMT2A
SCHEMBL14844098 0.70
SCHEMBL2093323 0.68 RAPGEF4 (0.43) RAPGEF4NOS3NOS1NOS2FFAR4
SCHEMBL8436212 0.68 CYP11B2 (0.39) HCAR2
SCHEMBL7968716 0.68 POLB (0.41) MEN1KMT2AHCAR2
SCHEMBL8438588 0.67 HCAR2 (0.36) HCAR2
SCHEMBL112244 0.67
SCHEMBL31171067 0.67
SCHEMBL7971923 0.67 CHRM5 (0.47) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed