Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971923 | 0.77 | CHRM5 (0.47) | MAPTKMT2ANFE2L2GRIN1GRIN2B | |
| SCHEMBL7223467 | 0.74 | CYP1A1 (0.39) | KMT2APADI4 | |
| SCHEMBL8436212 | 0.74 | CYP11B2 (0.39) | MAPTCYP11B1CYP11B2PADI4 | |
| SCHEMBL8488964 | 0.73 | VCP (0.40) | NPC1RAB9ACYP11B1CYP11B2 | |
| SCHEMBL7958570 | 0.71 | CYP11B2 (0.46) | LMNAHTTNPC1RAB9AKDM4E | |
| SCHEMBL7969830 | 0.71 | TP53 (0.43) | LMNAHTTNPC1RAB9AKDM4E | |
| SCHEMBL7968716 | 0.71 | POLB (0.41) | HTTNPC1RAB9AKDM4EMAPT | |
| SCHEMBL7958557 | 0.70 | RAF1 (0.32) | KMT2A | |
| SCHEMBL7222015 | 0.69 | ALDH1A1 (0.41) | LMNAHPGDMAPTKMT2ANFE2L2 | |
| SCHEMBL7974639 | 0.68 | CHRM5 (0.46) | NPC1RAB9AKDM4ENFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |