Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550571 | 0.82 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL31556483 | 0.76 | TRPV4 (0.44) | TRPV4ALDH1A1MAPK1HTT | |
| SCHEMBL788147 | 0.76 | TRPV4 (0.44) | TRPV4ALDH1A1MAPK1HTT | |
| SCHEMBL10600544 | 0.73 | CYP3A4 (0.38) | MAPK1HTT | |
| SCHEMBL16555423 | 0.71 | TRPV4 (0.40) | TRPV4EPAS1ALDH1A1HTT | |
| SCHEMBL3550070 | 0.71 | LMNA (0.43) | TRPV4EPAS1ALDH1A1MAPK1HTT | |
| SCHEMBL10532523 | 0.71 | TSHR (0.40) | TRPV4ALDH1A1MAPK1HTT | |
| SCHEMBL1596048 | 0.68 | TRPV4 (0.50) | TRPV4 | |
| SCHEMBL8764082 | 0.67 | TSHR (0.40) | TRPV4ALDH1A1MAPK1HTT | |
| SCHEMBL184577 | 0.67 | TRPV4 (0.40) | TRPV4ALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211181-B1 | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIALLERGENS, AND ANTIASTHMATICS | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-04-03 | — | — | US | disclosed |
| US-6080758-A | ANALGESICS, ANTIINFLAMMATORY AGENTS; ASTHMA; ALLERGIC RHINITIS | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-06-27 | — | — | US | disclosed |