SCHEMBL7959938

SCHEMBL7959938

Nc1ccc2c(-c3cc(C(=O)O)ccc3C(=O)O)c3ccc(=O)cc-3oc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 4/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
MEN1 O00255 2/20 0.54
POLB P06746 2/20 0.54
KMT2A Q03164 2/20 0.54
ALPL P05186 1/20 0.54
ALPI P09923 1/20 0.54
ALPG P10696 1/20 0.54
DNASE1L3 Q13609 1/20 0.53
PRMT1 Q99873 1/20 0.53
ATM Q13315 2/20 0.46
PLEC Q15149 1/20 0.46
CA9 Q16790 11/20 0.45
ABCB1 P08183 1/20 0.45
CA1 P00915 9/20 0.44
CA2 P00918 9/20 0.44
CFTR P13569 1/20 0.44
PAX8 Q06710 1/20 0.44
GOPC Q9HD26 1/20 0.44
ALB P02768 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7970059 0.92 USP2 (0.76) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL10082964 0.88 ABCB1 (0.59) USP2L3MBTL1MEN1POLBKMT2A
6-Carboxyfluorescein SCHEMBL9906208 0.88 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
6-Carboxyfluorescein SCHEMBL29369299 0.88 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL13384808 0.87 USP2 (0.85) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3430200 0.86 USP2 (0.74) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL7973529 0.84 USP2 (0.59) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL12604830 0.83 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3481432 0.81 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL30023431 0.81 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016128-A1 Rhodamine lactone phosphoramidites and polymers AAT BIOQUEST, INC. 2012-01-19 US disclosed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120016128-A1 Rhodamine lactone phosphoramidites and polymers PHYKPL, PFAS, PHOSPHO1 USP2 4450/4885L3MBTL1 790/4885MEN1 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.